Candida and Infertility

How Can Infertility Result from Candida Overgrowth

Approximately 35% of women with infertility are affected with post inflammatory changes of the oviduct or surrounding peritoneum that interfere with tubo-ovarian function. Most of these alterations result from infection. Symptomatic, asymptomatic or latent infections or their sequelae may also contribute to chronic inflammation of the cervix and endometrium, alterations in reproductive tract secretions, induction of immune mediators that interfere with gamete embryo physiology and structural disorders such as intrauterine synechiae.

Candida and Hyperthyroidism
About 90% of candida victims have low thyroid function and many thyroid deficiency symptoms are also typical candida overgrowth symptoms. Candida binds to thyroxine and renders it ineffective. So there is a connection between candida and thyroid problems.

There is also a connection between hormonal imbalance and hypothyroidism. Books on candidiasis have always stressed the connection between yeast overgrowth and endocrine dysfunction. Candida toxins seem to thrive on hormones produced by the endocrine system. The first of which is the adrenal glands, and this will affect the person’s ability to feel energised, cause the person to feel hot or cold temperatures easily, and sweat more than usual, heart palpitations, low sugar etc. Moving on to the thyroid gland, they affect the body’s metabolic rate. Serotonin levels are also affected; hence the mood swings.
Hypothyroidism is a condition in which the thyroid gland does not make enough thyroid hormone. Hypothyroidism or underactive thyroid is more common in women and people who are over 50. Low levels of thyroid hormone can interfere with ovulation, which impairs fertility.

Prevalence

The prevalence of hypothroidism in women of reproductive age is 2-4%. However, in a study conducted by Indu Verma, Renuka Sood, Sunil junega and Satinder Kaur, a total of 394 infertile women visiting the infertility clinic for the first time were investigated for throid stimulating hormone (TSH) and prolactin(PRL). Infertile women with hypothyroidism alone or with associated hyperprolactinemia were given treatment for hypothyroidism with thyroxine. Of the 394 infertile women, 23.9% were hypothyroid. After treatment, 76.6% of the infertile women conceived within 6weeks to 1 year.

References

Brooks, G.F., Carroll, K.C., Butel, J.S., Morse., S.A(1954). Jawetz, Melnick and Adelberg’s Medical Microbiology(25th ed.) McGraw-Hill, pp647-648

Clayton, S.G (2006). Gynecology by Ten Teachers, (14th ed.) Hodder Arnold H&S. pp262-263

Nester et al.,(2004). Microbiology: a Human Perspective (4th ed.) Boston:310 – 311

Novy, M., Eschenbach, D., Witkin, S.S (2008). Infections as a cause of infertility. Global Library of Women’s Medicine. DOI 10: 3843/GLOWN.10328

Scanlon V.C., Sanders, T(1991). Essentials of Anatomy and Physiology (4th ed.) pp459-476

Verma, I., Sood, R., Junega, S., Kaur, S (2012). Prevalence of hypothyroidism in infertile women and evaluation of response of treatment for hypothyroidism on infertility. International Journal of Applied and Basic Medical Research 2(1): 17-19

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